| 名稱 | TP53 p.H214R Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10215 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | TP53 p.H214R Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10215TP53 p.H214R Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10215 | |
| Format | Genomic DNA |
| Description | TP53 H214R lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). H214R results in increased IL-6 expression and colony formation compared to wild-type Tp53 in cell culture (PMID: 11920959), and is therefore predicted to confer a gain of function to Tp53. |
| Technical Data | |
| DNA Change | c.641A>G |
| AA Change | p.H214R |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 35.47% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM43687 |
| Chr position(GRCh37) | chr17:7578208 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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